Sistema Regional de Información
en línea para Revistas Científicas de América Latina,
el Caribe, España y Portugal

Introduction: The aim of this paper to elaborate a cost-benefit analysis to estimate the convenience of investing in a new prison within San Pedro Cholula, a municipality located in the Mexican Federal State of Puebla.                       Method: We use a methodology proposed by Canavagh P. David and Mark A.R. Kleinman (1990) who develop a cost-benefit analysis of building a prison in the United States considering four concerning participants: government, families, enterprises and society.                         Results: Based on an Internal Rate of Return of 48% and a cost-benefit relation of 1.77, it turns out that the construction of a new facility is convenient and recommendable under the present tenets.Conclusion: Overpopulation and precarious conditions prevail in most Mexican prisons nowadays. Corruption, violence and permanent violations of human rights are business as usual and the Cholula prison is not the exception. That is why, a new facility, away from the urban area is not only necessary but urgent, in order to improve the general conditions of the local population.

Introduction: We propose a novel approach for the assessment of the similarity of retinal vessel segmentation images that is based on linking the standard performance metrics of a segmentation algorithm, with the actual structural properties of the images through the fractal dimension.Method: We apply our methodology to compare the vascularity extracted by automatic segmentation against manually segmented images.Results: We demonstrate that the strong correlation between the standard metrics and fractal dimension is preserved regardless of the size of the subimages analyzed.Discussion or Conclusion: We show that the fractal dimension is correlated to the segmentation algorithm’s performance and therefore it can be used as a comparison metric.

Introduction: Mexico is the main producer of pricly pear in the world, with approximately 400,000 tons per year. However, it is a highly perishable fruit (9 to 15 days at room temperature), besides the presence of thorny hairs on its pericarpio limits consumption and limiting its commercialization which causes losses in its production. Therefore, it is necessary to propound for alternatives to be consumed as minimally processed product and the use of controlled atmospheres to extend its shelf life. Method: Different controlled atmospheres treatments (AC1: 5% O2 + 95% N2, AC2: Air + 10% CO2, AC3: 10% CO2 + 5% O2 + 85% N2 and air as control) were applied on minimally processed red prickly pear storaged at 5 ºC during 16 days. Sugars (S), total soluble solids (TSS), pH, polyphenol oxidase activity (PPO), physiological weight loss (PWL) and visual quality (VQ) were analized every four days.    Results: At the end of the storage period the treatments with controlled atmospheres showed the less physiological weight loss of pricly pear. The treatment with 10% CO2 + 5% O2 + 85% N2 highly contributed for the visual quality retention (6.24), physiological weight loss (9%) and pH (5.34), and the treatment with 10% CO2 + Air on the sugars content (176.21 mg Glucose mL-1); while the TSS and PPO enzyme activity did not differ between treatments. Also, the multivariate analysis of two principal components (PC) explained 85% of the variance, two components in six physicochemical variables of the pricly pear.Conclusion: The results show that controlled atmospheres can extend shelf life until 16 storage days when used on minimally processed prickly pear.

Sherlock Holmes, weekly magazine which was published between 1911 and 1913, was characterized by being the first publication dedicated exclusively to the chronicle and the police story in Buenos Aires. This feature makes it a privileged material to study how the field of gender conforms at the beginning of the 20th century. In this article, we intend to analyze how the journal contributed to the process of formation of a reading public fond of criminal fictions. In this sense, we consider that Sherlock Holmes was built, from the deployment of a number of different strategies, a reader model which, based on the perceptual matrix of the classic crime fiction, promoted the different ways of reading of the detective fiction reader.

NTRODUCTION: The timely diagnosis of HIV infection is a key strategy in the control of the epidemic. The use of rapid tests facilitates access to diagnosis at the primary care level and in spaces outside the health system. METHODS: The implementation process of the rapid test for HIV in Buenos Aires city was described, analyzing epidemiological indicators to assess the health impact. RESULTS: From the beginning of this strategy in 2012 and until 2018, the rapid test was implemented in 36 centers in the city, both in the health system and in civil society organizations. In 2014, a promotional campaign was started offering monthly testing in the public space of different neighborhoods. The number of people tested doubled in the testing centers and progressively increased in public hospital laboratories, with a decrease in the proportion of diagnoses in symptomatic stages. CONCLUSIONS: The implementation of the rapid test for the diagnosis of HIV in Buenos Aires city shows a successful model of offer of provision at the points of care, that facilitates access to screening and that can be extended for the diagnosis and treatment of other sexually transmitted infections

Introducción. Los factores genéticos del hospedero; como el polimorfismo de genes de citocinas influyen en la magnitud de la respuesta de anti-HBs inducida tras la vacunación contra el virus de la hepatitis B.Objetivos. Determinar si el polimorfismo de un simple nucleótido (SNP) de los genes de la interleucina 12 (IL12) A y B, influyen en la respuesta humoral a la vacuna Heberbiovac HB.Material y Métodos. Se estudiaron 12 trabajadores de la salud que no tenían niveles protectores de anti-HBs y fueron reactivados con una dosis de Heberbiovac HB. Las variantes de SNP de IL12A rs568408 e IL12B rs3212227 se identificaron por secuenciación nucleotídica. Se empleó el UMELISA anti-HBs para cuantificar los niveles de anti-HBs a los 7 y 28 días posteriores a la vacunación (dpv).Resultados. Altos niveles de anti-HBs (>1000UI/L) fueron detectados en el 75% (9/12) de los trabajadores a los 28dpv. Las combinaciones de IL12A rs568408/IL12B rs3212227 asociadas con una mayor respuesta de anti-HBs fueron la GG/AC y AG/AC. Bajos niveles protectores de anti-HBs (<13 UI/L) fue detectada a los 28 dpv, en un individuo que portaba la combinación AA/AA.Conclusión. La variabilidad genética entre individuos debe tenerse en cuenta para inducir una elevada seroprotección, en personas que reciban una dosis de reactivación con Heberbiovac HB.  

INTRODUCTION: Since 2016 laws on medicinalcannabis have been sanctioned and regulated. Cannabisis a psychoactive drug with hundreds of compounds, beingdelta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)those of greatest therapeutic interest. The objective of the presentwork was to describe the process of incorporation of cannabis indifferent provinces of Argentina. METHODS: The legal framework,scientific evidence, participation of decision makers and/or patients,NGOs, implementation protocols, agreements, import procedures,judicialization and current national regulations for the acquisition ofpreparations were analized. RESULTS: Between 2016 and 2017, fiveprovinces enacted laws on the medicinal use of cannabis, some ofthem carrying out mutual consultations and reporting on legislativeexperiences. In 2017, National Law No. 27350 was enacted, andpartially regulated. The use of CBD in refractory epilepsy is theindication with the greatest evidence of effectiveness in existingstudies, which is reflected in most of the laws. CBD preparations arenot legally marketed in the country, and must be imported by wayof exception and authorization from the National Administrationof Drugs, Foods and Medical Devices. CONCLUSIONS: A healthpolicy thar offers more benefit than risk is needed, as well as todocument the results in patients receiving treatments. RedAretshas presented a framework for explicit coverage, collaboratingin the elaboration of laws in their province&nbsp;&nbsp;

Chronic Noncommunicable Diseases (NCDs) are one of the leading causes of mortality and morbidity worldwide and three out of four deaths are attributed to avoidable risk factors. In Argentina, NCDs were responsible in 2015 for 73% of deaths in the country. In order to have scientific evidence to improve the adoption, coverage and effectiveness of prevention strategies and control of these diseases and their risk factors, and in the context of the implementation of the Universal Health Coverage, the Argentinian Government Secretary of Health (SGS), together with the Global Alliance for Chronic Diseases (GACD), has called for the presentation of research projects in implementation, for a term of two and three years, for an amount of up to $ 10,000,000, based on strategies for the prevention and control of hypertension, diabetes mellitus, smoking and cardio and cerebrovascular diseases, in vulnerable populations of Argentina. At the beginning of the call, 82 Conceptual Notes were received, of which 61 were rejected due to administrative requirements and 21 were reviewed by an External Evaluation Committee. After this instance, 12 of these notes were selected to present complete proposals. In January 2019, they were evaluated by an Evaluating Committee, made up of representatives of the GACD and the SGS. The projects approved to receive funding were four and will be developed from April 2019

This paper addresses the beginning of social policies in Argentina, in a historical period that covers approximately from 1880 until the advent of the first radical government of Hipólito Yrigoyen. To do this, it describes the model of the State instituted in Argentina during those years, the policies conceived in an assistance model and the institutions of that time that carried out specific interventions regarding the social universe. Within the set of institutions forged in the last decades of the nineteenth century, in response to the growing social tensions and as a product of various political, social, economic and cultural factors, it is interesting to address the role of the Charitable Society of Buenos Aires: the work carried out by this group of women belonging to the dominant sectors and their fields of intervention, which included the creation and management of health and mental health institutions (which constitutes a precedent in the management of public affairs, an area that at that time was reserved for the participation of men of ruling classes). The unprecedented action of these women, who burst onto the public stage, can retrospectively enable a gender perspective

The three great problems of surgery until the mid-nineteenth century were pain, deaths caused by infections, and hemorrhagic shock. The use of anesthetics drugs ended the intraoperative pain. Years later, antisepsis and asepsis were introduced, thanks to which surgeries did not ended in serious infectious conditions. However, deaths caused by hemorrhagic shock continued over the following years. The possibility of replacing the lost blood was still a problem without solution, for which different methods had been used, but all of them failed. In the beginning of the twentieth century, the discovery of the blood types enabled the first attempts of transfusion with certain safety; however, blood coagulated preventing the expected good result of the procedure from being reached. In 1914 Luis Agote, Argentine physician, researcher and politician, discovered the citrate method, making blood incoagulable; with the beginning of the First World War he performed the first transfusion, and this procedure then saved lives transfusing the wounded on the battlefields. Agote decided not to patent his discovery, since he was convinced that it belonged to the whole humanity