Sistema Regional de Información
en línea para Revistas Científicas de América Latina,
el Caribe, España y Portugal

Introduction: since ancient times, breast cancer has been studied. It is current the most important invasive neoplasm in women and considered the leading cause of cancer deaths in women worldwide. Objective: to assess the ultrasound, mammographic and histopathological correlation for the diagnosis of breast cancer in Guantanamo province. Method: an observational, descriptive, and retrospective study was conducted in 140 patients during the period 2010-2015 at the Hospital General Docente "Dr. Agostinho Neto" in Guantánamo. The primary information was obtained from the Provincial Registry Database of Cancer with the diagnosis of malignant breast tumor.Results: the highest incidence of the disease was recorded in patients 45 plus years of age (80%), the average age at diagnosis was 57 ± 15 years. The left breast was more frequently affected than the right breast (53% vs. 46%), it was not common for both breasts be affected synchronously (less than 1%). The 53% of patients presented a lesion with a speculated appearance on mammography, solid appearance on ultrasound. This lesion, as per histology criteria, it corresponded to an infiltrating ductal carcinoma. Conclusions: there is a correlation between ultrasound, mammographic diagnoses and the breast cancer related definitive histopathological diagnosis.

Introducción: las arbovirosis constituyen un grave problema sanitario en el Perú. Un mayor conocimiento y participación de la población en actividades preventivas puede minimizar su impacto.Objetivo: evaluar el nivel de conocimientos y su relación con las medidas preventivas sobre arbovirosis en estudiantes universitarios de una zona endémica del Perú, septiembre a noviembre de 2020.Método: se realizó un estudio observacional, transversal, correlacional y con diseño no experimental. La población estuvo conformada por 325 estudiantes de tecnología médica y la muestra por 176 estudiantes de ambos sexos. El nivel de conocimiento se categorizó en deficiente, regular y alto. Mientras que las medidas preventivas se clasificaron en adecuadas e inadecuadas. El cuestionario contenía 23 preguntas de opción múltiple, validadas por juicio de expertos. Resultados: El 69,9 % de los estudiantes presentó un nivel de conocimientos regular, observándose medidas preventivas inadecuadas en el 44,3 %. Un 92,0 % de encuestados consideró que las arbovirosis son enfermedades graves, pero solo 10,2 % reconoció el signo de alarma del zika. Las principales medidas preventivas fueron: la fumigación (50,6 %) y el uso de repelentes (49,6 %). Además, el 92,6 % de estudiantes consideró importante eliminar los criaderos de mosquitos para evitar la propagación de los arbovirus. Sin embargo, solo el 51,1 % revisó la presencia de criaderos y limpió diaria e interdiariamente su domicilio (43,8 %).Conclusiones: el nivel de conocimientos fue regular y se relacionó con medidas preventivas inadecuadas como no revisar frecuentemente la presencia de criaderos de mosquitos ni realizar limpieza en las viviendas.

Introducción: el cáncer bucal constituye un problema de salud de connotación mundial. Objetivo: comparar las variaciones del pH salival entre pacientes con carcinoma epidermoide recién diagnosticados, después del tratamiento oncoespecífico y sujetos aparentemente sanos de la provincia Guantánamo, Cuba, en el período noviembre 2019- enero 2022. Método: se realizó un estudio descriptivo, comparativo, transversal, en pacientes ambulatorios de la consulta de Cirugía Maxilofacial del Hospital General Docente “Dr. Agostinho Neto”. El grupo de estudio estuvo conformado por 200 pacientes divididos en 3 subgrupos: subgrupo I (50 pacientes recién diagnosticados con carcinoma epidermoide oral, con diagnóstico concomitante de caries dental y periodontitis crónica del adulto); subgrupo II (50 pacientes con la referida patología después de tratamiento oncoespecífico, tratados por las enfermedades bucales antes citadas) y subgrupo III (100 pacientes controles aparentemente sanos). Se estudiaron las variables: edad, sexo, tipo de dieta y pH salival. Resultados: la edad media fue de 59,8 años, 70 % fueron hombres. Se asoció la dieta consumida y cada subgrupo (p=0,001). El pH salival de los pacientes con carcinoma epidermoide recién diagnosticados afectados por ambas enfermedades bucales fue ácido (6,25±0,37) en comparación a los otros subgrupos. El 98,6 % de los pacientes con pH salival ácido presentaron una dieta usual a base de carbohidratos y grasas (p=0,000).Conclusiones: se evidenció que el pH salival de los pacientes con carcinoma epidermoide recién diagnosticados fue ácido en comparación a los otros subgrupos, por lo que este parámetro puede usarse como un marcador biológico de la enfermedad.

Introduction: the shock index has been proposed as an effective, cheap and easily achievable parameter for the prognosis of possible complications and even death. Objective: to describe the shock index values in patients admitted to Intensive Care Unit at the Hospital General Docente “Vladimir Ilich Lenin” de Holguín, Cuba, throughout June to December 2019. Method: a descriptive cross-sectional study was performed in which 98 patients (N=98) admitted to ICU were selected as universe, the sample consisted of 77 patients (n=77) through non-probabilistic sampling. Variables evaluated were as follow: APACHE II system, shock index, presumptive etiologic diagnosis, qSOFA score and serum lactate level. A data collection form was used as a research instrument. The SPSS version 24 statistical package was used. The mean and standard deviation were used to process the quantitative variables. Results: the predominant diseases found were postpartum hemorrhage, the postoperative complication and pre-eclampsia disorder. Serum lactate values were normal in 54.5% of studied patients and normal or low qSOFA values in 59.7%. The 84.2% showed low APACHE II values on admission and 58.5% had a shock index greater than 0.7.Conclusions: patients admitted to the ICU show greater alterations in the shock index than in better known and widely used variables like (APACHE II, qSOFA and serum lactate).

Introduction: arterial hypertension is a clinical condition that causes the admission of a large number of patients in the emergency and urgency areas of the hospital services. The number of hypertensive patients in the age group from 18 to 90 years of age is increasing in the João Paulo Basic Health Unit II, in Arame, Maranhão state. Objective: to implement an action plan for the optimal control of systemic arterial hypertension in the communities covered by the health institution under study, during the period from December 2017 to June 2018. Method: an intervention study was carried out in 467 hypertensive patients, out of a population of 935 individuals. The primary data was obtained from the medical records. The variables studied were: age, sex, toxic habits, body mass index, dietary habits, physical activity and compliance with medical treatment. Results: after the intervention, the attendance, treatment reassessment, admissions, and control of arterial figures improved substantially to 4.0%, 3.7%, 0.2%, and 9.8%, respectively.Conclusions: there is a need to intervene in the care of hypertensive patients and the general population to transform lifestyles and risk factors that guarantee the reduction of the incidence of systemic arterial hypertension, all of which favors the increase in adherence to treatment, improves medical follow-up and contributes to reducing complications and hospital admissions.

The use of Magnetic Resonance Imaging (MRI) in the diagnosis and follow-up of patients with Multiple Sclerosis (MS) has optimized the care of the affected patients. Several international working groups have tried to clarify and standardize the global use of MRI but, on many occasions, data are extrapolated from other regions, do not contemplate local realities or are difficult to implement. Objective: To reach a consensus on aspects related to the use of MRI in the diagnosis and follow-up of patients with MS in Peru. Material and Methods: A group of Peruvian experts (neurologists and radiologists) worked on the elaboration of the consensus using a remote survey round methodology. Results: The recommendations, established on the basis of published evidence and on the experts’ criteria, focused on the role of both, the conventional MRI techniques and the measurement of brain atrophy in MS patients both at the time of diagnosis and during the follow-up period. Conclusions: The consensual recommendations could potentially assist in the standardization and optimization of the care and follow-up of patients with MS in our country.

The health crisis caused by the Coronavirus Disease 2019 o COVID-19 pandemic, increases its contagiousness, and leaves millions of deaths, as well as significant consequences in the psychic sphere of affected people. Lockdown, mandatory quarantine, and the actions taken to reduce the number of infections lead to negative consequences for the mental health of university students. Objective: To identify the relationship between academic stress and generalized anxiety disorder caused by the COVID-2019 pandemic. Material and Methods: Descriptive-correlational study, using the Cognitive Systemic Inventory of Academic Stress (CSIAS) and the Scale for Generalized Anxiety Disorder (GAD-7), applied to 359 university students of Ecuador during the period May-June 2020. Results: From the total sample, 64.9% were women and 35.1%, men, with 43.7% in the 21-23 years-old group. In the CSIAS, the mean stress was higher in women (X = 3.4313) than in men (X = 3.2142), both groups presenting high levels of academic stress. On GAD-7, 51.5% of women presented symptoms of severe anxiety vs. 34.5% of men. A moderate positive correlation between academic stress and generalized anxiety was shown by a rho = 0.638. Conclusions: There are elevated levels of academic stress among university students, with women as the most affected group. A majority of probands of both genders showed symptoms of severe anxiety.

Dopa-responsive dystonia (DRD) encompasses a heterogenous group of primary dystonias, caused by enzymatic deficiencies across the amines pathway and, by definition, show as their main characteristic a favorable and sustained response to levodopa. There are up to 6 genes associated with DRD, including pathogenic variants of the GCH1 gene as the most frequently involved. The typical presentation of DRD is characterized by start in childhood, lower limb-onset dystonia with daytime fluctuation, mild parkinsonism, and a sustained response to low doses of levodopa. A systematic literature search on DRD reported cases in Latin America is presented.

The migration of millions of Venezuelans to South American countries in the last two or three decades is one of the most significant social phenomena in the continent’s history. This article presents a brief historical account of the process and describes a variety of dramatic aspects of the migrants’ experiences throughout the long road towards Colombia, Ecuador, Perú and other countries. The main socio-demographic characteristics of the migrant population (numbers, population types, geographic location in the host country, age, gender and civil status, work and employment) in the above three countries, are described as a relevant basis of further inquiries on the repercussions of migration on the mental health of its protagonists. The information covers important aspects of the journey and the arrival as the initiation of a painful and uncertain process of acculturation and adaptation.