Sistema Regional de Información
en línea para Revistas Científicas de América Latina,
el Caribe, España y Portugal

Objective: To discuss the relevance of pharmacological treatment for multiple sclerosis and highlight the importance of the pharmacist's role in therapeutic management. Methodology: The literature review was conducted using databases such as the CAPES Theses and Dissertations Catalog, The Scientific Electronic Library Online (SciELO), and Google Scholar. The inclusion criteria for the articles and studies selected were publications in Portuguese or English from the years 2019 to 2024. Results: The effectiveness of pharmacological treatments depends not only on the medications used but also on pharmaceutical support, which has proven essential for improving treatment adherence and minimizing adverse effects. Patient education about the disease and treatment is an area where pharmacists can make a significant difference. Conclusion: The pharmacist's role in managing multiple sclerosis is essential to optimize pharmacological treatment and ensure that patients receive the necessary support. The research underscores the importance of integrating pharmacists into the healthcare team, highlighting the need for further studies to deepen understanding of this role.

Objective: to describe the main motivating factors driving the use of Ozempic for weight loss. Methodology: The literature review was conducted using databases such as The Scientific Electronic Library Online (SciELO), Virtual Health Library (BVS), and PubMed, covering the years from 2019 to 2024. Results: suggest that the improper use of Ozempic is strongly linked to social pressure regarding beauty standards and the search for quick weight loss solutions. Factors such as self-esteem and social acceptance are key determinants in the behavior of individuals who use the medication without a medical prescription. Conclusion: a combination of social, cultural, and psychological factors significantly influences the inappropriate use of Ozempic as a weight loss strategy. The pharmacist is an essential professional in promoting the safe and effective use of the medication, reinforcing the importance of educational interventions and personalized guidance to prevent health risks.

Introduction: Hysterectomy, a procedure for surgically removing the uterus, has a history fraught with events obscured by the passage of time. There are accounts of its realization in 50 BC. by Themison of Athens and, later, by several other physicians, mainly in obstetric emergencies. Hysterectomy is currently the second most common gynecological surgical procedure performed among women of reproductive age in Brazil and has evolved into several types of procedures, each with its own benefits and limitations. According to DATASUS, in 2017, 49,121 surgeries were performed for total removal of the uterus by the Unified Health System. In this scenario, this study seeks to analyze the profile and trend of hysterectomies performed in Maranhão, through the Unified Health System (SUS), between 2011 and 2020. Methods: Descriptive and analytical cross-sectional study carried out in the state of Maranhão, using data available on the DATASUS online platform. Results: In the period considered in this study, 56,667 hospitalizations were registered for the procedure of removal of the uterus in residents of the state of Maranhão. There is an irregularity in the records and the absence of important variables for the socioeconomic analysis. The age group from 40 to 59 years old was the most representative in the sample (63.2%) and the most prevalent race/color was brown (46.2%). The most frequent procedure was total hysterectomy (62.63%), followed by hysterectomy with adnexectomy (23.86%) and vaginal hysterectomy (5.68%). Among the diagnoses, uterine leiomyomatosis predominated (63.7%), followed by malignant neoplasms of the uterus (9%) and endometriosis (7.13%). The data collected, in general, are in line with the available literature. Conclusion: Drawing an epidemiological profile that accurately describes the socioeconomic and clinical aspects of the population undergoing surgery is challenging, as records in hospital databases or secondary data sources are not uniform and lack a variety of information.

Introduction: The Human Immunodeficiency Virus, known as HIV, is the causative agent of acquired immunodeficiency syndrome (AIDS), a condition that compromises the immune system, especially CD4+ T cells. The virus modifies the DNA of cells, promoting its replication. Objective: to carry out an analysis of the existing literature, aiming to map information about the benefits of using zidovudine as a method to inhibit viral load in pregnant women with HIV. Methodology: employs the scoping review protocol according to the guidelines outlined in the Joanna Briggs Institute evidence syntheses manual (2020), which incorporates the following steps: formulation of the research question, identification of relevant studies, selection of studies to be included, extraction of relevant data, consolidation, synthesis and presentation of results. Results and discussion: it showed that the use of zidovudine in the treatment of HIV infection in pregnant women was worrying due to the various toxic effects presented, such as mitochondrial dysfunction, bone marrow suppression and cardiac toxicity. Conclusion: Based on the studies analyzed, zidovudine demonstrated to be an effective tool when used in combination with other antiretroviral agents to reduce the HIV viral load in pregnant women, significantly contributing to the prevention of vertical transmission of the virus to newborns.

Objective: To investigate the relationship between different types of continuous and intermittent renal replacement therapy and clinical outcomes in critically ill patients with acute kidney injury. Method: An integrative review was conducted using the following databases: Scopus (Elsevier), Latin American and Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online (Medline®/PubMed®), and Science Direct. The search focused on articles published between 2017 and 2023. The review was conducted between April and June 2023, adhering to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. Results: Seven articles were included, with the majority published in 2021, and China being the country with the highest prevalence. Regarding the level of evidence, most articles were classified as 2B. Continuous renal replacement therapy (CRRT) was found to be associated with better outcomes in terms of renal function recovery compared to intermittent renal replacement therapy (IRRT). Conclusion: Consistent evidence indicates that CRRT offers significant advantages over IRRT, particularly in terms of improved renal recovery, reduced risk of complications, and lower mortality rates.

The objective of this study was to reflect on the importance of breastfeeding as well as the challenges in obtaining health care aimed at socially vulnerable breastfeeding women in the light of Habermas' theory. This is a reflective study according to Habermas' theory. The results demonstrated that communicative action is an intrinsic part of nursing work in the breastfeeding process in the context of social vulnerability. For nursing, communication is a fundamental tool for carrying out activities, as it is through communication that the patient's needs are identified in order to plan the actions and interventions to be carried out. Therefore, Habermas' theory of communicative action can contribute to improving care for breastfeeding women in social vulnerability, since, by presenting their attitudes towards communicative action, the nurse will provide greater interaction with women in the lactation period as well as coping to the challenges of this phase

Effectively building an inclusive school for all is a challenge. For this reason, there are many uncertainties about how to promote and develop strategies that meet the needs of all students. Based on this understanding, a study was carried out that sought to analyse how digital information and communication technologies (DICTs) can be an ally in inclusive education practices in basic education with the help of Active Methodologies. In order to meet this objective, a bibliographical survey was carried out that addressed the topic, guided by the following specific objectives. Firstly, an analysis was made of the relationship between the processes involving globalisation and the expansion of cyberculture today. Subsequently, we analysed the benefits of the conscious use of TDICs and the way in which Active Methodologies can enhance inclusion in basic education through TDICs. Based on this study, it was observed that Active Methodologies are efficient strategies that can collaborate in the use of TDICs as tools that encourage student protagonism from the perspective of inclusive education for all.

This article addresses a brief reflection on a controversial issue in the educational field, concerning the challenges of Youth and Adult Education (EJA) from the perspective of public policies regarding the training of teachers working in secondary education. In order to reverberate the discussion of the proposed theme, the methodological route was to immerse ourselves in the scientific literature to seek contributions from authors and legal documents that could corroborate the topic. We use indicative observation with the aim of investigating whether EJA's public policies offer continued training for teachers working in secondary education. In the search for bibliographic sources, the strategy was based on the following keywords: “Youth and Adult Education”; “high school”; “teacher training”; “public policies”; For this purpose, the Google Scholar platform was used as a database. Considering the findings revealed in the bibliographical review, based on indicative observation, it was possible to perceive that public educational policies are still timid in offering continued training for educators and in keeping young people and adults in the educational system, in addition to other demands that exist in this modality, such as school dropout and class closures, are challenges still faced today in Brazil. At this moment, the National Pact for Overcoming Illiteracy and Qualification of Youth and Adult Education appears, bringing the hope of meeting the challenges faced by this modality, and could be the key piece for advancement in Brazilian education.  Keywords: Youth and Adult Education. Teacher training. Public Policies. National Pactto enhance EJA.

The objective of this scientific research is to conduct a systematic review of the international literature concerning performance evaluation related to the internationalization process of technology industries. The Knowledge Development Process – Constructivist (Proknow-C) was employed as a tool for the structured identification of relevant international literature on the research axes. Among the main findings of the analysis, it was observed that the number of publications on the subject has increased in recent years, that the majority of publications originate from European countries, that the most cited article has 177 citations, and that the most influential author in the bibliographic portfolio (BP) is Joan Freixanet, with two articles. Additionally, the author network in the BP comprises 63 occurrences. This study contributes to academia by providing a comprehensive overview of the literature related to the research axes.    

The 1988 Federal Constitution symbolizes an indelible milestone in Brazilian history, enabling a new configuration in the field of the right to education and a new arrangement in the scope of educational financing. The 1988 Constitution represents a fundamental evolution in these two areas because it guarantees the right to education according to national guidelines and establishes rules for the financing of public education. This article aims to contribute to the expansion of the debate regarding the relationship between the right to education and educational financing from the promulgation of the 1988 Federal Constitution until 2016. It seeks to highlight the role of the 1988 Constitution in securing resources for education, particularly basic education, as well as to point out the developments in the Citizen Constitution that provided critical provisions for the areas of the right to education and educational financing up until 2016, such as FUNDEF, FUNDEB, FIES, PROUNI, and CAQi. Through bibliographical research, we aim to indicate the milestones achieved in the right to education and educational financing based on the 1988 Constitution, in addition to raising awareness about the challenges that these two areas still need to face.