Sistema Regional de Información
en línea para Revistas Científicas de América Latina,
el Caribe, España y Portugal

Introduction: Intestinal parasites are a highly prevalent disease worldwide and locally, they are widely distributed in the different regions of our country. In the Andean zone, there is a higher prevalence of protozoan parasites in relation to helminths. Objective: To determine the prevalence of intestinal parasites in elementary students from District 7, Viacha on April 2017. Methods: A descriptive, observational, cross-sectional and prospective study was developed where 122 students were considered as a representative sample of the population, after signing an informed consent by their tutors. Fecal stool samples were collected and the analysis was carried out through simple coproparasitological examination in the microbiology and parasitology laboratory of the Nursing School of the Universidad Pública de El Alto. Results: A prevalence of intestinal parasites of 59% (n = 72) was found, being the most found pathogenic species G. intestinalis (9.84%) and among commensals B. hominis and E. coli (34.43% for each case). Likewise, cases of parasitic associations such as biparasitism (n = 24) and tryparasitism (n = 2) could be evidenced. Regarding the distribution of parasitosis according to gender and age groups, it was possible to show that the most affected gender was the male (p <0.05) and there was no difference between the age groups (p = 0.638). Conclusion: A high prevalence of intestinal parasitosis was found in students from District 7, Viacha.

Introduction: COVID-19 pandemic has been a miscellaneous event, affecting individuals’ perception as subjects and intersubjective relations, the state as a referent of representation/identity was disrupted, and health/disease conditions were externalized as results of social relations, Mood disorders, social marking and fear are predictable effects, which is why knowing available validated instruments to study them becomes relevant. Main objective: Asses the validity of DASS-21, FCV-19S y the COVID-19 Stigma questionnaire in urban Bolivian setting. Method: This paper examines the validity of three instruments: DASS-21, FCV-19S and a Spanish translation of the COVID-19 Stigma questionnaire, for urban Bolivian context, on a pilot study in Cochabamba city comprised by 30 randomized subjects, based on Cronbach’s alpha and factorial analysis. Results: After considering context, internal consistency and validity was found on DASS-21 and Stigma questionnaire, under sociodemographic conditions similar to those of the pilot. Conclusion: the validated instruments are apt to apply in Bolivia, with proper considerations to optimize effectiveness.

Humanization of healthcare personnel is an increasingly important approach in modern healthcare. Humanization involves treating patients as unique individuals, not just as medical cases. Humanization of healthcare personnel involves fostering empathy, compassion and effective communication in medical care.

Correct installation of a biochemical analyzer depends on compliance with the manufacturer's specifications. The manufacturer of the Vitros 4600 biochemical analyzer (OrthoClinicalDiagnostics), which quantifies analytes based on the dry chemistry method, guarantees its good analytical performance up to 2438 masl. If the installation is carried out at higher altitudes, the clinical laboratory must apply experimental protocols that demonstrate that the performance of the analyzer has clinical validity. Objective: To evaluate the analytical performance of dry chemistry in a clinical laboratory located at high altitude (Huancayo-Peru, 3259 masl). Methodology: Application and longitudinal study. The CLSI protocol EP15-A2 was applied as a reference of standardized procedures to calculate the SD and CV (random error) as well as the bias (systematic error) for two concentration levels of some routine analytes such as glucose, urea, creatinine, triglycerides and AST, using Bio Rad third part controls. From the data obtained, the sigma metric was calculated as an indicator of analytical performance for each analyte, using CLIA criteria of total acceptable error. Results: Sigma metrics were obtained, higher than 4 for all the analytes, finding performances: good for urea, very good for glucose and excellent for creatinine, AST and triglycerides. Conclusion: Dry chemistry was shown to have acceptable analytical performance, despite being used at an altitude higher than the manufacturer's specifications.

Revista Científica Ciencia Médica publica artículos originales, artículos de revisión, artículos especiales, casos clínicos, imágenes en medicina, cartas al editor, educación médica continua y editoriales; el manuscrito debe subirse a la plataforma OJS y debe enviarse una copia al correo de la revista: revcienciamedica@gmail.com; una vez enviado el autor recibirá un e-mail confirmando la recepción del mismo. Los manuscritos deben estar relacionados al campo de las ciencias de la salud y serán evaluados y aceptados para su publicación a juicio del comité editorial y su cuerpo de asesores, según su contenido, relevancia, originalidad , impacto y contribución científica del tema, siguiendo la política editorial del peer review a doble ciego. En caso de que los revisores consideren necesario hacer modificaciones, los autores serán contactados por correo electrónico. Originalidad: no publicada en otro país o idioma, no presentada simultáneamente a más de una publicación sin que los editores hayan acordado la co-publicación señalándolo en el texto, sujeta a las leyes de propiedad intelectual citando fuentes primarias identificables.

The main cause of mortality in chronic kidney disease (CKD), in 80% of patients, is due to associated cardiovascular disease, the classic biochemical parameters of bone-mineral metabolism will not yet be able to explain the pathological progression, therefore, new markers have begun to be studied in relation to cardiovascular damage, where the marker FGF-23 and its co-receptor Klotho have been found, involved in the genesis of cardiovascular damage and bone-mineral disease associated with phosphorus, which together cause cardiovascular remodeling , which has begun to further clarify this pathophysiological dynamic.This review seeks to know the implication of the FGF-23 and Klotho markers in CKD and the associated cardiovascular risk and for this purpose, a systematic review of the literature was carried out, investigating biomedical bases such as COCHRANE, Embase, LILACS, Scielo, Pub-Med, EBSCO, Hinari, Medical Societies, as well as MeSH thesauri specific to this research.

La enterocolitis de tipo alérgica es una reacción no mediada por inmunoglobulina E producida por la proteína de leche de vaca, muestra un cuadro clínico grave caracterizado por: vómitos y diarrea profusa, palidez, letargia, acidemia, distensión abdominal y shock. Se presenta el caso de un neonato de 19 días de vida, con ingesta de fórmula maternizada y posterior desarrollo de síntomas compatibles con enterocolitis alérgica, presentó criterios de reproducibilidad y empeoramiento con mejoría clínica al retiro de fórmula maternizada. Su incidencia es sumamente desconocida e inusual en el periodo neonatal y en muchos casos suele ser confundida con la enterocolitis necrotizante. Sin embargo, debe ser considerada en las posibilidades diagnósticas por tratarse de un cuadro grave y manejo diferente.

Cancer’s development is determined by the proliferative capacity of tumor cells and by presenting invasive abilities and to metastasize to distant tissues. The complex relationship of this pathology with the immune system facilitates its natural evolution; thus, this bidirectionality allows cancer cells to escape from the host's regulation, evading antitumoral immune responses, through intrinsic and extrinsic mechanisms. The aim of this manuscript is to describe exhaustively, and in the most updated way possible, said mechanisms, with the objective of generating a tangible impact and more awareness the medical-scientific community, regarding the genesis of possible new and more specific diagnostic and treatment options that diminish this lethal disease’s statistics. The information used to write this article was obtained from medical digital archives, including PubMed, Google Scholar, Scielo, and Elsevier, as well as specialized books in immunology and immunopathology, and articles published in the last five years.

Introduction: Introduction: The Covid-19 pandemic is a Public Health problem, which affects people with vulnerability, such The Covid-19 pandemic is a Public Health problem, which affects people with vulnerability, such as people with HIV/AIDS, in order to know their behavior and improve prevention and control strategies, it is as people with HIV/AIDS, in order to know their behavior and improve prevention and control strategies, it is necessary to evaluate the perception of risk and severity they have. necessary to evaluate the perception of risk and severity they have. Objective: Objective: To determine the perception of risk and severity of Covid-19 in people living with HIV and who To determine the perception of risk and severity of Covid-19 in people living with HIV and who attends to medical controls at the Departmental Center for Surveillance, Information and Reference (CDVIR) attends to medical controls at the Departmental Center for Surveillance, Information and Reference (CDVIR) of the city of Cochabamba. of the city of Cochabamba. Methods: Methods: A cross-sectional, quantitative study was carried out between 327 people living with HIV who attended A cross-sectional, quantitative study was carried out between 327 people living with HIV who attended the CDVIR between May and June 2021. A survey was applied with risk perception and severity questions taken the CDVIR between May and June 2021. A survey was applied with risk perception and severity questions taken from the survey “Covid-19

Clinically COVID-19 presents with flu-like symptoms and respiratory distress with or without hypoxia that can progress in severity, which partially responds to the presence of SARS-CoV-2 variants that would be responsible for heterologous reinfections. This case shows a sequence of four infections with time intervals between each infection of around 5 months coinciding with the periods in which four waves of infection occurred in Bolivia. The Covid-19, during the third episode was more severe than the previous ones with lung involvement, increased C-Reactive Protein and liver damage. It is assumed that such a situation responds to a heterologous infection with a variant different from the previous two and the possibility of development of the ADE phenomenon.