Sistema Regional de Información
en línea para Revistas Científicas de América Latina,
el Caribe, España y Portugal

Gastrointestinal stromal tumors (GIST) are mesenchymal neoplasms that represent less than 3% of gastrointestinal neoplasms, with an incidence of 1 to 2 cases per hundred thousand inhabitants. It originates more frequently in the stomach and small intestine and is characterized by the expression of the tyrosine kinase growth factor receptor, CD117. Therefore, its diagnosis requires an immunohischemical study to rule it out from other mesenchymal tumors. However, enteroscopic imaging and analysis of the biopsy may suggest a preoperative diagnosis of probable GIST. The case of a 62-year-old woman with rectorrhagia and recurrent anemia caused by mid-intestinal bleeding observed by capsule endoscopy is reported. Enteroscopy revealed a subepithelial ulcerated lesion in the proximal jejunum, and a biopsy was taken, the anatomopathological study of which suggested a gastrointestinal stromal tumor. The biopsy sample subjected to immunohistochemical studies confirms the suspicion of a cKit/CD117-positive GIST tumor. Surgical resection of the tumor with dimensions 4.2x3 cm is performed. After surgery, the patient was stable and under clinical follow-up until she was discharged. Clinical finding

Breast cancer continues to be one of the main priorities in global health and public health, and remains the most frequent and deadly malignant neoplasm in women worldwide. Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare type of non-Hodgkin's lymphoma, whose pathogenesis and pathophysiology are not well known, but which is seen with increasing frequency due to the increase in cosmetic procedures. To date, there are limitations in terms of knowledge about the clinical behavior of the disease, which can manifest itself in many forms, with a variable evolution time and uncertain surgical outcomes in the medium- and long-term. Based on the above, the aim of this review is to summarize evidence on the clinical considerations and surgical outcomes of breast implant-associated cancer to facilitate the identification and management of this condition. A bibliographic search was performed in the search engines and databases PubMed, ScienceDirect, Embase, EBSCO and MEDLINE. Within the clinical and surgical considerations, the type of implant used (textured), the time of the implant history, the severity of the manifestations, and the staging, must be taken into account in order to determine the opportunity for surgical intervention and neoadjuvant therapy, and to try to guarantee survival and avoid recurrence. Patients who undergo complete capsulectomy with radiotherapy have better outcomes.

Introduction: Older adults are susceptible to malnutrition and vitamin deficiency. Objective: To determine the association between the low level of vitamin B12 and cognitive deterioration in older adults from the Naval Medical Center, located in Lima-Peru, in the period 2010-2015. Methods: An analytical cross-sectional study was carried out, based on a secondary analysis of the Texas-Cemena UTMB 2010-2015 database of the Center for Research on Aging (CIEN) of the University of San Martín de Porres. To quantify the cognitive impairment variable, the MiniMental Test was used. To analyze the association, the Chi-square test and Poisson regression were performed. Results: 57.6% of the patients were male and the mean age was 78 ± 8.4. 41.2% presented cognitive deterioration and 9.5% of the patients presented vitamin B12 deficiency. The factors independently associated with cognitive impairment were a history of cerebrovascular disease (PR= 1.38 95% CI [1.24-1.53]), depression (PR= 1.88 95% CI [1.80-1 .97]) and vitamin B12 deficiency (PR = 1.10 95% CI [1.01-1.20]). Conclusions: In the present study, an association was found between a low level of vitamin B12 and cognitive deterioration in older adults.

Objective: To determine the sociodemographic and clinical characteristics associated with positive attitudes towards sexuality in older adults seen in the outpatient clinic of the Hipólito Unanue National Hospital from september to december, 2021. Methods: Cross-sectional analytical observational study, which included 227 adult patients over 60 years of age from the outpatient clinic of the HNHU geriatrics service attended by teleconsultation. Attitudes towards sexuality were measured by applying the Questionnaire of Attitudes towards Sexuality in Older Adults, dividing the result into positive and negative attitudes. Results: 86.3% of older adults have a positive attitude towards sexuality, the age of 60 to 79 years was presented in 73% of these patients, higher education was higher in the group with positive attitude (47%), 53.6% of the patients with a positive attitude reported having a current partner, having received educational talks increases the probability of a positive attitude towards sexuality by 3.12 times. In the bivariate analysis, there was a statistically significant association between age 60 to 79 years (RP: 1.31, 95%CI: 1.12-1.52, p<0.001), higher education (RP: 1.19, 95%CI: 1.08-1.31, p=0.001), having a current partner (RP: 1.32, 95%CI: 1.19-1.46, p<0.001), having received educational talks (RP: 1.13, 95%CI: 1.03-1.24, p=0.033). In the multivariate analysis, an association was found between having a current partner and a positive attitude towards sexuality (RPa: 1.177, 95%CI: 1.09-1.26, p<0.001). Conclusion: There is a high frequency of positive attitude towards sexuality in older adults, and having a current partner was an independent associated factor.

Introduction: Quality of life is one of the main concerns for cancer patients in palliative care; however, studies on quality of life in these patients are limited. Objective: To determine the factors associated with quality of life in patients with oncological disease in palliative care. Methods: Observational, analytical study in 184 cancer patients treated in a Pain and Palliative Care Unit during 2021. The dependent variable was quality of life; independent variables were age, sex, education level, occupation, oncological diagnosis, disease duration, and stage. Crude (RP) and adjusted (aRP) prevalence ratios were calculated with a 95% confidence level. Results: The median age was 63 years, and 66.3% were female. Factors associated with quality of life were breast cancer (aRP=1.21; 95% CI: 1.07-1.36; p<0.010), prostate cancer (aRP=1.36; 95% CI: 1.18-1.56; p<0.010), or multiple myeloma (aRP=1.33; 95% CI: 1.15-1.53; p<0.010), compared to other cancers such as Hodgkin's lymphoma, stomach, kidney, or pancreatic cancer; disease duration longer than 36 months (aRP=1.13; 95% CI: 1.01-1.27; p=0.040), and stage III (aRP=1.30; 95% CI: 1.19-1.42; p<0.010) were also associated with quality of life. Conclusions: Factors associated with quality of life were having breast, prostate, or multiple myeloma cancer, compared to having another type of cancer; in addition to a disease duration longer than 36 months and stage III compared to stage I/II.

Objective: To analyze risky eating behaviors in relation to nutritional status and physical activity in young adults during the COVID-19 pandemic in the communes of Chillán and Chillán Viejo. Methods: Observational and cross-sectional design. A sample of 184 young adults of both sexes, who lived in two communes in the Ñuble region (Chile) during the period of confinement due to COVID-19 pandemic, was obtained. A personal history questionnaire and the SCOFF scale that assesses the risk of eating behavior disorders (EDs) were applied. Results: A 37.16% risk for ED was found (95% CI: 30.23 – 44.63%). The risk of eating behavior disorders was related to the variables: physical activity (p=0.01 bivariate analysis) and nutritional status (p=0.03, adjusted analysis). Conclusion: It was possible to identify a higher proportion than that recorded in the literature and the factors associated with eating disorders were those that were expected to be found.

Objective: To determine the relationship between work environment and job satisfaction of nursing staff in the emergency service of Hospital de Vitarte.  Methods: Quantitative, correlational and cross-sectional research. The population and sample consisted of 70 members of the nursing staff of the emergency service. With the prior informed consent of each participant, two questionnaires validated in other studies were applied through a survey.  Results: The participating nursing staff was mainly between 30 and 39 years old (50%), was female (62,9%), with the same number of professionals and technicians, with a slight predominance of contracted (51,4%) and had between 6 to 10 years of service. The dimensions of the work environment: self-realization (81,4%), work involvement (82,9%), supervision (82,9%) and communication (54,3%) were considered moderately favorable; working conditions were unfavorable (42,9%). The dimensions of satisfaction: physical conditions - materials (81,43%), administrative policies (72,86%) were unsatisfactory; while in social benefits – remuneration (87,14%), social relationships (47,14%), personal development (65,71%), task development (72,86%) and performance beyond the position (80%) were moderately satisfactory. The work environment was considered moderately favorable (48,57%) and job satisfaction was moderately satisfactory (42,86%).  Conclusions: A statistically significant relationship was found between work environment and job satisfaction (p=0,023) in the nursing staff in the emergency service of the Hospital de Vitarte.

Objective: The objective of this study was to determine the sociocultural factors in 50-year-old users for Pap smears at the Ricardo Cruzado Rivarola de Nasca hospital during the period December 2021 - February 2022.  Material and Methods: Observational, analytical, and prospective study. The study population is made up of 80 50-year-old users who attend the Ricardo Cruzado Rivarola hospital for Pap tests at the gynecology-obstetrics office and the sample is 67 users, selected by non-probabilistic sampling for convenience.  Results: For the first analysis, in simple and multiple regression, it was found that women with a high level of knowledge had a 384% and 382% higher frequency of having ever undergone a PAP, compared to those with a low level of knowledge.  Conclusions: The level of knowledge about the PAP has a relevant influence on having carried out a PAP; but also the women who had a high level were the ones who had the highest frequency of having done it. This added to the number of children; possibly because in the circles of women with children one of the topics to be discussed is about maternal health and within them the PAP.

Introduction: University social responsibility is present in the discourses of academics, but it fails to permeate the actions that lead to the transformation of the university, requiring a paradigm shift. At present there are conceptual confusions that make its promotion and transformative practice very difficult, in many universities it is confused with social projection, which reduces its transversal dimension.  Objective: To analyze the scientific evidence related to university social responsibility in Latin America.  Methods: Systematic review of the literature, between the months of August to December 2021; the search for articles was carried out in the databases: Scopus, Scielo, Doaj, Lilacs and Redalyc; the use of Descriptors in Health Sciences (DeCS) and the combination of the Boolean operators OR and AND were applied. Full texts in Spanish between the years 2015 and 2021 were considered.  Results: 508 articles were obtained, which were submitted to the PRISMA methodology, selecting 20 articles, grouped into four categories according to the Social Responsibility Manual of the Úrsula Model: management, training, cognitive, and social participation.  Conclusions: USR is an inalienable moral commitment, it is important in university management to promote sustainable development, with ethics and respect for human rights, the participation of committed actors is necessary, considering that it currently has a welfare and reductionist approach, scarce support, socialization and implementation and there is a need to unify criteria.

Introduction: In Peru, 78.1% of women between the ages of 15 and 49 use a contraceptive method, which is diminished by various factors associated with non-adherence to the contraceptive method, thus producing unwanted pregnancies and the spread of sexually transmitted diseases. Objective: To determine the factors associated with non-adherence to contraceptive methods in women of childbearing age in Peru according to ENDES 2021. Methods: Observational, analytical and cross-sectional study. The information used is found in the ENDES 2021 public database. The population of this research is made up of Peruvian women between the ages of 15 and 49. Statistical analysis was performed with the statistical program SPSS version 26.0. The qualitative variables were represented in a univariate table with frequencies and coefficients of variation. The approved statistical significance value was p <0.05 with 95% confidence intervals. Results: 43.7% of women did not adhere to the contraceptive method. There was a significant association for the variables: area of rural residence (Rpa 1.05 IC 1 – 1.1), separated marital status (Rpa 1.1, IC 1 – 1.1), widow marital status (Rpa 1.3, IC 1.1 – 1.5), cohabiting marital status ( Rpa 1.1, IC 1.1 – 1.2) , poor wealth index (Rpa 1.03, IC 0.9 – 1.0) Conclusions: The factors associated with non-adherence to contraceptive methods in women of childbearing age in Peru, which are significantly associated are: Rural area of residence, separate marital status, widow and cohabitant and have a poor wealth index.