Sistema Regional de Información
en línea para Revistas Científicas de América Latina,
el Caribe, España y Portugal

Introducción: la diabetes mellitus constituye un serio problema de salud en Cuba y en el mundo. Una de sus complicaciones más frecuentes es la úlcera del pie diabético asociada a alteraciones neurológicas, vasculares e infecciosas. Con el descubrimiento del heberprot-P se presenta un nuevo tratamiento para la úlcera del pie diabético que se extiende y fortalece en el Sistema de Salud.Objetivo: describir los resultados del uso del heberprot-P® en las úlceras del pie diabético.Métodos: se realizó un estudio observacional, descriptivo, longitudinal en pacientes atendidos en el Policlínico Docente “Capitán Roberto Fleites” en el período comprendido desde enero a diciembre de 2019. Se estudiaron 43 pacientes con tratamiento con heberprot-P, se tuvieron en cuenta la edad, el sexo, el tipo de diabetes mellitus, el grado de afectación según la clasificación de Wagner, la dosis y el número de aplicaciones y la evaluación de la respuesta al tratamiento.Resultados: en el estudio predominaron los pacientes comprendidos entre los 61 y los 80 años de edad (65,12%), el sexo masculino (55,81%) y la diabetes tipo 2 (55,81%); el 74,42% de los pacientes necesitó entre cinco y 10 aplicaciones; se logró una granulación completa en el 83,72% de los casos y no se requirió amputación.Conclusiones: la administración del heberprot-P en las úlceras del pie diabético resulta efectiva al lograr una alta cicatrización y evitar las amputaciones.

Introduction: incorporating functional aspects and the study of the temporomandibular joints (TMJ) to the orthodontic field, requires an initial examination of the TMJ, and from that position in centric relation (CR), make a diagnosis and plan the orthodontic treatment.Objective: to determine the possible association between slides from CR to the position of maximum intercuspation (PMI) with age, and to identify changes in occlusal variables as a consequence of the slide.Methods: a descriptive and correlational cross-sectional study was carried out, in the period from October 2018 to October 2019, at the Victoria de Santa Clara Teaching Clinic of Stomatological Specialties. An intentional, non-probabilistic sample of 30 young people between 15 and 19 years of age, with complete permanent dentition and abnormal sliding from RC to PMI, was formed. Occlusal variables were examined: projections, overhangs, relationship of molars and canines, dental midlines.Results: the mean of the magnitude of the anterior slip between CR and PMI showed a value of 1.53mm, highlighting adolescents of 15 years of age; while in the lateral slide the distribution behaved homogeneously. With a magnitude of 1 mm or more, the three mean values of overjets differed significantly, with p<0.05 in incisors and p<0.10 in canines. The right molar ratio changed significantly between CR and PMI, with p=0.046.Conclusions: the discrepancy between CR and PMI was not associated with age. Changes in occlusal variables confirm the importance of performing a correct occlusal examination for orthodontic diagnosis and treatment.

Introduction: uterine sarcomas are a diverse group of rare mesenchymal (mesodermal) neoplasms with a range of characteristics depending on histologic subtype and tumor grade.Objective: to characterize clinically and anatomopathologically the malignant mesenchymal tumors of the uterus that were diagnosed in the Department of Pathological Anatomy of the “Mariana Grajales” Hospital in the period from January 2010 to December 2017.Methods: a developmental, descriptive, observational and cross-sectional research was conducted at the Gynecobstetric Hospital “Mariana Grajales” in the period from September 2015 to September 2018. The study population was constituted by all patients who underwent excisional biopsy in the period from January 2010 to December 2017, with a diagnosis of malignant mesenchymal tumor.Results: endometrial stromal sarcoma, leiomyosarcomas and adenosarcomas predominated. Smooth muscle tumors, endometrial stromal tumors and mesenchymal miscellaneous tumors predominated in premenopausal women, whereas mixed tumors predominated in postmenopausal women.Conclusions: sarcomas were most frequently present in the uterine body, with a polypoid growth pattern. The poor prognostic factors showed significant values. Epithelioid leiomyosarcomas were large in size, and lymphovascular invasion was not evident in the majority of tumors. Endometrial stromal tumors were predominantly low mitotic index, with little invasion into the myometrium.

Introduction: chronic kidney disease affects a great part of the population in the world. Its diagnosis in the initial stages allows a better management of the disease, better prognosis and better quality of life.Objective: to compare the health status of patients with chronic kidney disease at the time of starting hemodialysis according to the influence of early or late remission to the Nephrology Specialist.Methods: a descriptive and cross-sectional observational study was carried out on a population of 348 patients who started renal replacement therapy in hemodialysis at the "Arnaldo Milián Castro" Hospital during the study period; the Chi-square distribution was used for statistical analysis.Results: there was a predominance of male patients, older than 60 years old, with a late referral to hemodialysis. In 40.8% of the cases the cause was diabetes and 65.56% of the late referrals required an urgent dialysis. In both study groups were showed alterations in hemochemistry values and glomerular filtration rate and albumin were those with more variability. Patients with tardy referral were those who presented more comorbidities and 51.5% were not dispensed.Conclusions: patients with a late remission to the Nephrology Specialist are those who most need emergency hemodialysis and emergency temporary vascular access, as well as those who most often have hypertension associated with their underlying disease, and most of them are not seen by their family doctor.

Introduction: fear is a common problem that Stomatology Specialists face daily, it can affect patient management and treatment effectiveness.Objective: to characterize fear before stomatological treatment in eight and nine year old children.Methods: a cross-sectional descriptive study was carried out at the “Chiqui Gómez” Polyclinic from January to September 2020. A sample of 162 children selected through simple random sampling was obtained. A Scale of Dental Fears in Children and an Observation Guide were applied.Results: fear predominated in nine-year-old male children. It was shown that the greater the fear, the greater the frequency of attitudes associated with this emotion.Conclusions: it was shown that more fear was associated with older age, and that the male sex was more fearful. There was a significant relationship between fear and associated attitudes.

Introduction: primary cutaneous B-cell lymphoma is a rare neoplastic proliferation of immunophenotype B lymphocytes; its pathogenic mechanisms are unknown.Patient information: a 77-year-old male patient is presented, who approximately three months ago started with erythematous-violaceous, infiltrated, multifocal plaques, located on the posterior trunk, in addition to a violaceous tumor, with neoformation vessels on its surface, which was accompanied by weight loss. He was evaluated multidisciplinary and after biopsy of the lesion and staging studies it was concluded asDiffuse lymphoma of primary cutaneous large B-cell. Polychemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisone and monoclonal antibody: rituximab was indicated as treatment, with favorable evolution.Conclusions: this disease, even being unfrequent, with a good prognosis and relatively easy therapeutic management, should be suspected and diagnosed in time; the connotations that its diagnosis and treatment imply for the patient should not be forgotten.

Introducción: el líquido seminal es la combinación de líquido de la próstata y otras glándulas sexuales que permiten el transporte del esperma durante la eyaculación. Contiene azúcar como fuente principal de energía. Su composición es relevante porque puede dar indicios de problemas de salud o de infertilidad, por lo que su estudio en el laboratorio clínico o de andrología debe garantizar un resultado confiable mediante el empleo de métodos estandarizados.Objetivo: evaluar la calidad de la determinación de la concentración espermática en la prueba de espermatobioscopía directa en los laboratorios clínicos de acuerdo al Manual de la Organización Mundial de la Salud para el análisis y el procesamiento del semen humano.Métodos: se realizó una investigación de tipo observacional, descriptivo, longitudinal y prospectivo en 23 laboratorios clínicos entre septiembre de 2017 y mayo de 2018 con riesgo mínimo, nivel II y de acuerdo con el Reglamento de la Ley General de Salud en materia de Investigación en Salud.Resultados: diversas condiciones ponen de manifiesto la deficiencia en el análisis de la concentración espermática: falta de capacitación (65,2%), de instructivos (60,9%), de procedimientos (69,6%), de calibración de equipos de medición y de apoyo, como pipetas automáticas (69,6%). Las pruebas de Spearman (rs=0,753402; NC:95%; rs<0,05) y Kendal Tau (t=0,707696; NC:95%; t<0,05) no fueron significativas para el tiempo de funcionamiento de los laboratorios clínicos y las pruebas de Mann-Whitney y Kruskal-Wallis mostraron diferencias significativas (U: p=0,037887; NC=95%; p<0,05/KW: p=0,000000; NC=95%; p<0,05) respecto a las lecturas de la concentración espermática.Conclusiones: más del 60% de los laboratorios carecen de un proceso adecuado para el análisis del líquido seminal

Introduction: renal lithiasis is very common, the predominant symptom is pain, generally intense, which must be alleviated, and homeopathic treatment is an option accessible to everybody.Objective: to evaluate the results of homeopathic treatment with calcareous carbonic 30CH indicated in patients diagnosed with renal lithiasis.Methods: a prospective longitudinal descriptive study was carried out in adult patients with a diagnosis of renal lithiasis attended at the Urology Service of the "Arnaldo Milián Castro" Hospital of Villa Clara Province during the years from 2017 to 2020. They were included 220 patients willing to cooperate with the study and were indicated treatment with calcareous carbonic 30CH.Results: female sex (115, 52.3%), age between 30 and 44 years (78, 35.5%), rural origin (129, 58.6%), consumption of well water (168, 76.4%), presentation with pain, nausea and vomiting, left lithiasis - in most cases (115, 52, 37 patients expelled the calculus in less than 30 days and 140 in the second month of treatment, 210 patients were cured, with 213 negative ultrasound scans, in the remaining patients the symptoms were relieved and the size of the lithiasis was reduced, there were few complications.Conclusions: the results of cure in more than three quarters of the patients treated confirm the use of 30CH carbonic calcarea as another option in the treatment of renal lithiasis.

Introduction: drug consumption has increased in the last decades and precisely pregnancy represents a situation of maximum risk related to its use.Objective: to describe maternal factors and drug consumption during pregnancy associated with the appearance of neonatal alterations.Methods: a retrospective longitudinal descriptive study was conducted in the period from September 2015 to September 2018 to describe maternal factors and medication consumption during pregnancy associated with the appearance of neonatal alterations. The study population consisted of 779 pregnant women recruited during this period and the sample consisted of 518 randomly selected pregnant women. We worked with two groups: one group of pregnant women who did not consume drugs during pregnancy and the other who did. The data obtained made it possible to analyze maternal variables such as the consumption of drugs during pregnancy, the area of origin of those who consumed them, the drugs prescribed or not and the trimester of pregnancy in which they were consumed and, for the newborn, the presence or absence of neonatal alterations.Results: the frequency of medication consumption during pregnancy was 55.21%.Conclusions: in the sample studied, the consumption of drugs during pregnancy prevailed, mainly in the first trimester, mostly by self-medication in women from rural areas, and neonatal alterations were significantly associated with all the above mentioned.

Introducción: en edades pediátricas la incidencia de la lesión renal aguda asociada a las enfermedades infecciosas es alta. Se considerada potencialmente prevenible y se presenta con elevadas morbilidad y mortalidad.Objetivo: caracterizar a los pacientes pediátricos con lesión renal aguda.Métodos: se realizó un estudio en un Centro de hemodiálisis en Angola con una población de 60 pacientes pediátricos evaluados en el período de mayo de 2017 a mayo de 2020. La información se tomó del proceso clínico del hospital y del centro de diálisis.Resultados: predominaron los pacientes masculinos, con edades superiores a 10 años. Su etiología estuvo en relación con la malaria y el síndrome nefrótico. Los principales síntomas fueron los neurológicos y por sobrecarga de volumen.Conclusiones: requirieron tratamiento renal de remplazo de tipo hemodiálisis la mayoría de los pacientes, con una evolución satisfactoria y una baja mortalidad.